Effective January 3, 2017, the “RPR” test code will be replaced with a highly sensitive and specific screening algorithm for Syphilis. The traditional RPR test will be replaced with a Treponemal Antibody test which will be performed on an automated immunoassay platform. Positive or equivocal antibody tests will then reflex to “RPR with Titer” as a confirmatory method at an additional charge. If RPR results are negative, a second Treponemal antibody test method will be performed at an additional charge.
Benefits of this change include:
- Consistent with recommendations by CDC and other professional organizations.
- Decrease in false positive results as compared to RPR testing because the test measures antibodies specific to the organism (T. palladium) that causes syphilis.
- Automated immunoassay with recombinant antigens further increases specificity.
- RPR reflex is provided to aid in diagnosis and to monitor therapy, because a positive antibody test does not distinguish treated and untreated infections.
- A second, different antibody method is provided to help resolve discordant results between reactive (positive) antibody and nonreactive RPR.
- A more sensitive treponemal assay allows for measureable improvement in the early detection of syphilis infection.
|TEST NAME||CPT CODE||REFERENCE RANGE|
|Trepoema palladium Ab||86780||Nonreactive|
|T. palladium Ab by
chemiluminescent immunoassy (CLIA)
If you have any questions, please call our Client Service department at 877-883-8783.
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